With our Biocatalytic Drug Optimization platform, bacteria are used in addition to traditional chemistry to install new positions on drug scaffolds for analog synthesis. This platform results in the following benefits:
- Metabolic sites are blocked resulting in PK improvement.
- Fewer analogs are needed in the drug optimization process.
- New IP is readily produced.
- Excellent fit with our drug optimization programs.
Figure: Traditional and biocatalytic analog synthesis positions on a steroid scaffold.